Blood Research

Brief details of the cases with two concurrent genetic abnormalities.

Case No. Genetic abnormalities detected Modified Rai/Binet stage Management Time to treatment
5 Trisomy 12+CDKN2D-2(19p13.2) deletion Intermediate/B Chemotherapy 1 mo
15 13q14.2-3 deletion+CDKN2D-2(19p13.2) gain Low/A Observation -
21 13q14.2-3 deletion+trisomy 12 High/C Observation -
39 Trisomy 12+NOTCH1(p.P2514*fs) mutation Intermediate/B Chemotherapy 2 mo
53 13q14.2-3 deletion+CDKN2D-2(19p13.2) gain High/C Chemotherapy 3.5 mo
76 13q14.3 deletion+17p13.1 deletion Low/A Lost to follow-up
Blood Res 2020;55:131~138 https://doi.org/10.5045/br.2020.2020080
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