Fig. 1. Proposed treatment algorithm in relapsed and refractory multiple myeloma patients. Abbreviations: DRd, daratumumab-Rd; DVd, daratumumab-Vd; ERd, elotuzumab-Rd; IMiD, immunomodulatory drug; IMWG, international myeloma working group; IRd, ixazomib-Rd; Kd, carfilzomibdexamethasone; KRd, carfilzomib-Rd; LDH, lactate dehydrogenase; M protein, monoclonal protein; PCd, pomalidomide-cyclophosphamide, dexamethasone; Pd, pomalidomide, dexamethasone; PI, proteasome inhibitor; Rd, lenalidomide-low-dose dexamethasone; Vd, bortezomibdexamethasone.

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