Blood Research

World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia.

WHO classification of myeloid neoplasms and acute leukemia
Acute myeloid leukemia (AML) and related neoplasms
AML with recurrent genetic abnormalities
AML with t(8;21)(q22q22.1); RUNX1-RUNX1T1
AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22);CBFB-MYH11
APL with PML-RARA
AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3
AML with t(6;9)(p23;q34.1); DEK-NUP214
AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2); GATA2, MECOM
AML (megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1
Provisional entity: AML with BCR-ABL1
AML with mutated NPM1
AML with biallelic mutation of CEBPA
Provisional entity: AML with mutated RUNX1
AML with myelodysplasia-related changes
Therapy-related myeloid neoplasms
AML, not otherwise specified (NOS)
AML with minimal differentiation
AML without maturation
AML with maturation
Acute myelomonocytic leukemia
Acute monoblastic and monocytic leukemia
Pure erythroid leukemia
Acute megakaryoblastic leukemia
Acute basophilic leukemia
Acute panmyelosis with myelofibrosis
Myeloid sarcoma
Myeloid proliferations associated with Down syndrome
Transient abnormal myelopoiesis (TAM) associated with Down syndrome
Myeloid leukemia associated with Down syndrome
Blood Res 2020;55:S1~S4 https://doi.org/10.5045/br.2020.S001
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