Conventional FCXM results with neat sera from multiparous recipients against T cells or B cells from previous sensitizers, and criteria to differentiate the DSAs between class I and class II.
| FCXM | N (%) | Criteria using MFI ratios | ||
|---|---|---|---|---|
| Determination | T cell | B cell | B cell/T cell | |
| Negative DSA | 69 (48.3) | <2.0 | <2.0 | |
| Positive DSA | 74 (51.7) | |||
| Class I alone | 14 (9.8) | >2.0 | >2.0 | <2.0 |
| Class II alone | 27 (18.9) | <2.0 | >2.0 | |
| Class I and II | 33 (23.1) | >2.0 | >2.0 | >2.0 |
| Total | 143 (100) | |||
Abbreviations: DSA, donor-specific HLA alloantibody; FCXM, flow cytometric crossmatch; MFI, mean fluorescence intensity.
Blood Res 2020;55:91~98 https://doi.org/10.5045/br.2020.2020031
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