Patient characteristics.
N | % | |
---|---|---|
Age, years | ||
Median (range) | 34 (22–79) | |
Age≥65 | 4 | 20 |
Sex | ||
Male | 13 | 65 |
Female | 7 | 35 |
Histology | ||
Nodular sclerosis | 9 | 45 |
Mixed cellularity | 6 | 30 |
Subtype indeterminate | 5 | 25 |
ECOG performance status | ||
0 | 12 | 60 |
1 | 5 | 25 |
2 | 3 | 15 |
EBV in-situ hybridization | ||
Negative | 6 | 30 |
Positive | 7 | 35 |
Unknown | 7 | 35 |
B symptom | ||
No | 18 | 90 |
Yes | 2 | 10 |
Stage | ||
I | 1 | 5 |
II | 4 | 20 |
III | 6 | 30 |
IV | 9 | 45 |
Extranodal involvement | ||
Lung | 9 | 45 |
Bone | 7 | 35 |
Liver | 2 | 10 |
Prior ASCT | 7 | 35 |
Prior radiotherapy, No. | 4 | 20 |
Prior brentuximab vedotin, No. | 12 | 60 |
Prior chemotherapies, No. | ||
1–3 | 14 | 70 |
≥4 | 6 | 30 |
Abbreviations: ASCT, autologous hematopoietic stem cell transplantation; EBV, Epstein-Barr virus; ECOG, eastern cooperative oncology group.