Identified DNMT3A mutations in 28 patients with acute myeloid leukemia.

^a)non-sense mutation.

Abbreviations: AML, acute myeloid leukemia; Fs, frame shift mutation; MTase, methyltransferase; PWWP, P (proline)-W (tryptophan)-W (tryptophan)-P(proline) motif; ZNF, zinc finger.