Fig. 2. Immunophenotyping of the neoplastic cells in bone marrow aspirate at the time of diagnosis by four-color flow cytometry (dot-plot analysis). CLL/SLL cells (sky-blue) showing characteristic phenotype: CD5+, CD23+, sIgweak+, CD20weak+ and CD10- whereas HCL cells (purple) showing CD20bright+, CD25+, CD103+, CD11cbright+, sIg+, CD23-, CD5-, and CD10-.

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