One-stage clotting factor assay. Factor activity in healthy males, pre- and post-infusion of factor concentrates in hemophilia A and B patients (A). In-vivo recovery of hemophilia A and B patients (B).

Abbreviations: FL-FVIII, full-length factor VIII; IVR, in-vivo recovery; pdFVIII, plasma-derived factor VIII; rFVIII, recombinant factor VIII.