Identification and selection of studies for steroid-refractory chronic graft-versus-host disease (SR-cGVHD). Default criteria for cGVHD diagnosis were based on the NIH consensus criteria as below: Diagnosis of cGVHD requires the presence of at least 1 diagnostic clinical sign of cGVHD or the presence of at least 1 distinctive manifestation confirmed by pertinent biopsy or other relevant tests in the same or another organ [13].