The distribution of factor VIII activity levels of the carriers and non-carriers of 2 common polymorphisms Asp1260Glu (A) and Ser1288=(B) among the control individuals. The upper/lower ends and the inner lines of the boxes correspond to the upper/lower quartiles and median values, respectively. Circles represent factor VIII activity values. The lines from each box extend from the minimum to the maximum values, excluding outlying values displayed as a separate circle.