Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation

Prasad Iyer; Peter Carey; Nick Bown; Sujith Samarasinghe

doi:10.5045/br.2013.48.2.151

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Blood Res 2013; 48(2):

Published online June 25, 2013

https://doi.org/10.5045/br.2013.48.2.151

Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation

Prasad Iyer^1*, Peter Carey¹, Nick Bown², and Sujith Samarasinghe¹

Author Info. +

¹Department of Paediatric and Adolescent Oncology, The Great North Children's Hospital, Royal Victoria Infirmary, UK.

²Cytogenetics Laboratory, Northern Genetics Service, UK.

Correspondence to : Prasad Iyer. Department of Paediatric and Adolescent Oncology, The Great North Children's Hospital, Royal Victoria Infirmary, Newcastle Upon Tyne, NE1 4LP, UK. drprasad_iyer@yahoo.co.uk

Received: May 17, 2013; Accepted: May 1, 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

FIGURES

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FIGURES
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Fig. 1.

Blood film demonstrating chronic myeloid leukemia in lymphoid blast transformation.

Fig. 2.

(A) Karyotype showing t(9;22)(q34;q11) Philadelphia translocation. (B) Interphase FISH, Vysis dual-fusion probe set. Green: BCR; red: ABL1; yellow: fused BCR and ABL signals corresponding to der(9) and der(22) translocation products.

REFERENCES

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FIGURES
REFERENCES

Ries LAG, Smith MA, Gurney JG. Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. Bethesda, MD: National Cancer Institute.
Millot, F, Traore, P, Guilhot, J, et al. Clinical and biological features at diagnosis in 40 children with chronic myeloid leukemia. Pediatrics, 2005;116;140-143.
Vardiman, JW, Harris, NL, Brunning, RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood, 2002;100;2292-2302.
Andolina, JR, Neudorf, SM, Corey, SJ. How I treat childhood CML. Blood, 2012;119;1821-1830.

Article

Letter to the Editor

Blood Res 2013; 48(2): 151-152

Published online June 25, 2013 https://doi.org/10.5045/br.2013.48.2.151

Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation

Prasad Iyer^1*, Peter Carey¹, Nick Bown², and Sujith Samarasinghe¹

¹Department of Paediatric and Adolescent Oncology, The Great North Children's Hospital, Royal Victoria Infirmary, UK.

²Cytogenetics Laboratory, Northern Genetics Service, UK.

Correspondence to: Prasad Iyer. Department of Paediatric and Adolescent Oncology, The Great North Children's Hospital, Royal Victoria Infirmary, Newcastle Upon Tyne, NE1 4LP, UK. drprasad_iyer@yahoo.co.uk

Received: May 17, 2013; Accepted: May 1, 2013

Fig 1.

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Figure 1.

Blood film demonstrating chronic myeloid leukemia in lymphoid blast transformation.

Blood Research 2013; 48: 151-152https://doi.org/10.5045/br.2013.48.2.151

Fig 2.

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Figure 2.

Blood Research 2013; 48: 151-152https://doi.org/10.5045/br.2013.48.2.151

References

Ries LAG, Smith MA, Gurney JG. Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. Bethesda, MD: National Cancer Institute.
Millot, F, Traore, P, Guilhot, J, et al. Clinical and biological features at diagnosis in 40 children with chronic myeloid leukemia. Pediatrics, 2005;116;140-143.
Vardiman, JW, Harris, NL, Brunning, RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood, 2002;100;2292-2302.
Andolina, JR, Neudorf, SM, Corey, SJ. How I treat childhood CML. Blood, 2012;119;1821-1830.