SitemapContact Us
닫기
Search
Advanced Search +
닫기
Quick links
Most Cited Most Read Ahead of Print Archives Go to E-submission

Letter to the Editor

Split Viewer

Blood Res 2015; 50(4):

Published online December 31, 2015

https://doi.org/10.5045/br.2015.50.4.262

© The Korean Society of Hematology

Bilateral Parotid MALToma: a sure shot for radiation

Babusha Kalra1*, Pamela Alice Kingsley1, Preety Negi1, M Joseph John2, Kanwardeep Kwatra3, and Uttam Braino George4

Author Info. +

1Department of Radiotherapy, Christian Medical College and Hospital, Ludhiana, India.

2Department of Clinical Hematology and Hemat Oncology, Christian Medical College and Hospital, Ludhiana, India.

3Department of Pathology, Christian Medical College and Hospital, Ludhiana, India.

4Department of Radiology, Christian Medical College and Hospital, Ludhiana, India.

Correspondence to : Babusha Kalra. Department of Radiotherapy, Christian Medical College and Hospital, Brown Road, Ludhiana, Punjab 141008, India. kalrababusha@gmail.com

Received: January 7, 2015; Revised: October 26, 2015; Accepted: November 5, 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

FIGURES

Go to
Fig. 1.

(A) Left parotid swelling measuring 5.8×4.2×4 cm at initial diagnosis. (B) Complete clinical response after radiotherapy.


Fig. 2.

Contrast enhanced T1- weighted axial and coronal magnetic resonance imaging showing a 5.8×4.2×4 cm lesion replacing the left parotid gland and a 3×2×2 cm lesion in the right parotid gland (A, C). T2-weighted axial and coronal images showing homogenously hyperintense lesions in both parotid glands (B, D).


Fig. 3.

(A) Expanded pale looking marginal zone (arrows) surrounding a lymphoid follicle (LF), H&E ×100. (B) Marginal zone cells with round to slightly irregular nuclei and moderate amount of pale cytoplasm, H&E ×400. (C) to (F) Immunohistochemistry showing a CD20+, CD10-, CD23- and CD5-neoplastic lymphoid cells. DAB chromogen ×400.


REFERENCES

Go to
  1. Harris, NL, Jaffe, ES, Stein, H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood, 1994;84;1361-1392.
    Pubmed
  2. Thieblemont, C, Berger, F, Dumontet, C, et al. Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood, 2000;95;802-806.
    Pubmed
  3. Balm, AJ, Delaere, P, Hilgers, FJ, Somers, R, Van Heerde, P. Primary lymphoma of mucosa associated lymphoid tissue (MALT) in the parotid gland. Clin Otolaryngol Allied Sci, 1993;18;528-532.
    Pubmed
  4. Mehle, ME, Kraus, DH, Wood, BG, Tubbs, R, Tucker, HM, Lavertu, P. Lymphoma of the parotid gland. Laryngoscope, 1993;103;17-21.
    Pubmed
  5. Ciccone, E, Truini, M, Grossi, CE. Lymphoid complement of the human salivary glands: function and pathology. Eur J Morphol, 1998;36;252-256.
    Pubmed
  6. Diss, TC, Wotherspoon, AC, Speight, P, Pan, L, Isaacson, PG. B-cell monoclonality, Epstein Barr virus, and t(14;18) in myoepithelial sialadenitis and low-grade B-cell MALT lymphoma of the parotid gland. Am J Surg Pathol, 1995;19;531-536.
    Pubmed
  7. Marioni, G, Marchese-Ragona, R, Marino, F, et al. MALT-type lymphoma and Warthin's tumour presenting in the same parotid gland. Acta Otolaryngol, 2004;124;318-323.
    Pubmed
  8. Rosenstiel, DB, Carroll, WR, Listinsky, CM. MALT lymphoma presenting as a cystic salivary gland mass. Head Neck, 2001;23;254-258.
    Pubmed
  9. Anacak, Y, Miller, RC, Constantinou, N, et al. Primary mucosa-associated lymphoid tissue lymphoma of the salivary glands: a multicenter Rare Cancer Network study. Int J Radiat Oncol Biol Phys, 2012;82;315-320.
    Pubmed
  10. Ferri, C, Caracciolo, F, Zignego, AL, et al. Hepatitis C virus infection in patients with non-Hodgkin's lymphoma. Br J Haematol, 1994;88;392-394.
    Pubmed
  11. Ando, M, Matsuzaki, M, Murofushi, T. Mucosa-associated lymphoid tissue lymphoma presented as diffuse swelling of the parotid gland. Am J Otolaryngol, 2005;26;285-288.
    Pubmed
  12. Perry, C, Herishanu, Y, Metzer, U, et al. Diagnostic accuracy of PET/CT in patients with extranodal marginal zone MALT lymphoma. Eur J Haematol, 2007;79;205-209.
    Pubmed
  13. Tsai, HK, Li, S, Ng, AK, Silver, B, Stevenson, MA, Mauch, PM. Role of radiation therapy in the treatment of stage I/II mucosa-associated lymphoid tissue lymphoma. Ann Oncol, 2007;18;672-678.
    Pubmed
  14. Wenzel, C, Fiebiger, W, Dieckmann, K, Formanek, M, Chott, A, Raderer, M. Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue of the head and neck area: high rate of disease recurrence following local therapy. Cancer, 2003;97;2236-2241.
    Pubmed
  15. Zinzani, PL, Magagnoli, M, Ascani, S, et al. Nongastrointestinal mucosa-associated lymphoid tissue (MALT) lymphomas: clinical and therapeutic features of 24 localized patients. Ann Oncol, 1997;8;883-886.
    Pubmed

Article

Letter to the Editor

Blood Res 2015; 50(4): 262-264

Published online December 31, 2015 https://doi.org/10.5045/br.2015.50.4.262

Copyright © The Korean Society of Hematology.

Bilateral Parotid MALToma: a sure shot for radiation

Babusha Kalra1*, Pamela Alice Kingsley1, Preety Negi1, M Joseph John2, Kanwardeep Kwatra3, and Uttam Braino George4

1Department of Radiotherapy, Christian Medical College and Hospital, Ludhiana, India.

2Department of Clinical Hematology and Hemat Oncology, Christian Medical College and Hospital, Ludhiana, India.

3Department of Pathology, Christian Medical College and Hospital, Ludhiana, India.

4Department of Radiology, Christian Medical College and Hospital, Ludhiana, India.

Correspondence to: Babusha Kalra. Department of Radiotherapy, Christian Medical College and Hospital, Brown Road, Ludhiana, Punjab 141008, India. kalrababusha@gmail.com

Received: January 7, 2015; Revised: October 26, 2015; Accepted: November 5, 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Fig 1.

    Download
    Figure 1.

    (A) Left parotid swelling measuring 5.8×4.2×4 cm at initial diagnosis. (B) Complete clinical response after radiotherapy.

    Blood Research 2015; 50: 262-264https://doi.org/10.5045/br.2015.50.4.262

    Fig 2.

    Download
    Figure 2.

    Contrast enhanced T1- weighted axial and coronal magnetic resonance imaging showing a 5.8×4.2×4 cm lesion replacing the left parotid gland and a 3×2×2 cm lesion in the right parotid gland (A, C). T2-weighted axial and coronal images showing homogenously hyperintense lesions in both parotid glands (B, D).

    Blood Research 2015; 50: 262-264https://doi.org/10.5045/br.2015.50.4.262

    Fig 3.

    Download
    Figure 3.

    (A) Expanded pale looking marginal zone (arrows) surrounding a lymphoid follicle (LF), H&E ×100. (B) Marginal zone cells with round to slightly irregular nuclei and moderate amount of pale cytoplasm, H&E ×400. (C) to (F) Immunohistochemistry showing a CD20+, CD10-, CD23- and CD5-neoplastic lymphoid cells. DAB chromogen ×400.

    Blood Research 2015; 50: 262-264https://doi.org/10.5045/br.2015.50.4.262

    References

    1. Harris, NL, Jaffe, ES, Stein, H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood, 1994;84;1361-1392.
      Pubmed
    2. Thieblemont, C, Berger, F, Dumontet, C, et al. Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood, 2000;95;802-806.
      Pubmed
    3. Balm, AJ, Delaere, P, Hilgers, FJ, Somers, R, Van Heerde, P. Primary lymphoma of mucosa associated lymphoid tissue (MALT) in the parotid gland. Clin Otolaryngol Allied Sci, 1993;18;528-532.
      Pubmed
    4. Mehle, ME, Kraus, DH, Wood, BG, Tubbs, R, Tucker, HM, Lavertu, P. Lymphoma of the parotid gland. Laryngoscope, 1993;103;17-21.
      Pubmed
    5. Ciccone, E, Truini, M, Grossi, CE. Lymphoid complement of the human salivary glands: function and pathology. Eur J Morphol, 1998;36;252-256.
      Pubmed
    6. Diss, TC, Wotherspoon, AC, Speight, P, Pan, L, Isaacson, PG. B-cell monoclonality, Epstein Barr virus, and t(14;18) in myoepithelial sialadenitis and low-grade B-cell MALT lymphoma of the parotid gland. Am J Surg Pathol, 1995;19;531-536.
      Pubmed
    7. Marioni, G, Marchese-Ragona, R, Marino, F, et al. MALT-type lymphoma and Warthin's tumour presenting in the same parotid gland. Acta Otolaryngol, 2004;124;318-323.
      Pubmed
    8. Rosenstiel, DB, Carroll, WR, Listinsky, CM. MALT lymphoma presenting as a cystic salivary gland mass. Head Neck, 2001;23;254-258.
      Pubmed
    9. Anacak, Y, Miller, RC, Constantinou, N, et al. Primary mucosa-associated lymphoid tissue lymphoma of the salivary glands: a multicenter Rare Cancer Network study. Int J Radiat Oncol Biol Phys, 2012;82;315-320.
      Pubmed
    10. Ferri, C, Caracciolo, F, Zignego, AL, et al. Hepatitis C virus infection in patients with non-Hodgkin's lymphoma. Br J Haematol, 1994;88;392-394.
      Pubmed
    11. Ando, M, Matsuzaki, M, Murofushi, T. Mucosa-associated lymphoid tissue lymphoma presented as diffuse swelling of the parotid gland. Am J Otolaryngol, 2005;26;285-288.
      Pubmed
    12. Perry, C, Herishanu, Y, Metzer, U, et al. Diagnostic accuracy of PET/CT in patients with extranodal marginal zone MALT lymphoma. Eur J Haematol, 2007;79;205-209.
      Pubmed
    13. Tsai, HK, Li, S, Ng, AK, Silver, B, Stevenson, MA, Mauch, PM. Role of radiation therapy in the treatment of stage I/II mucosa-associated lymphoid tissue lymphoma. Ann Oncol, 2007;18;672-678.
      Pubmed
    14. Wenzel, C, Fiebiger, W, Dieckmann, K, Formanek, M, Chott, A, Raderer, M. Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue of the head and neck area: high rate of disease recurrence following local therapy. Cancer, 2003;97;2236-2241.
      Pubmed
    15. Zinzani, PL, Magagnoli, M, Ascani, S, et al. Nongastrointestinal mucosa-associated lymphoid tissue (MALT) lymphomas: clinical and therapeutic features of 24 localized patients. Ann Oncol, 1997;8;883-886.
      Pubmed
    Blood Res
    Volume 59 2024
    Current Issue Archives

    Stats or Metrics

    Share this article on

    • line

    Blood Research

    pISSN 2287-979X
    eISSN 2288-0011
    qr-code Download