Korean J Hematol 2003; 38(3):
Published online September 30, 2003
© The Korean Society of Hematology
비전형 만성골수성백혈병의 골수성 아세포기 1례
조희순, 이채훈, 김경동, 이경희, 배성화, 조덕, 양동욱
영남대학교 의과대학 내과학교실,
영남대학교 의과대학 진단검사의학교실,
대구가톨릭대학교 의과대학 내과학교실,
전남대학교 의과대학 진단검사의학교실
A Case of Myeloid Blast Crisis of Atypical Chronic Myelogenous Leukemia
Atypical chronic myelogenous leukemia (aCML) has dysplastic as well as proliferative features in most instance and rarely evolves to blast crisis, so it is considered as a distinct clinical entity to classical BCR-ABL (+) CML. We experienced a patient who are diagnosed aCML and transformed to myeloid blast crisis after 17 months. Monosomy 7 and deletion of 12p were found on conventional cytogenetics.
Keywords Atypical chronic myelogenous leukemia; Myeloid blast crisis; Monosomy 7; Deletion of 12p
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Korean J Hematol 2003; 38(3): 200-204
Published online September 30, 2003
Copyright © The Korean Society of Hematology.
비전형 만성골수성백혈병의 골수성 아세포기 1례
조희순, 이채훈, 김경동, 이경희, 배성화, 조덕, 양동욱
영남대학교 의과대학 내과학교실,
영남대학교 의과대학 진단검사의학교실,
대구가톨릭대학교 의과대학 내과학교실,
전남대학교 의과대학 진단검사의학교실
A Case of Myeloid Blast Crisis of Atypical Chronic Myelogenous Leukemia
Hee Soon Cho, Chae Hoon Lee, Kyung Dong Kim, Kyung Hee Lee, Sung Hwa Bae, Duck Cho, Dong Wook Tyang
Department of Laboratory Medicine, Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea
Department of Internal Medicine, Daegu Catholic University College of Medicine, Korea
Department of Laboratory Medicine, Chonnam University Medical School, Kwangju, Korea
Abstract
Atypical chronic myelogenous leukemia (aCML) has dysplastic as well as proliferative features in most instance and rarely evolves to blast crisis, so it is considered as a distinct clinical entity to classical BCR-ABL (+) CML. We experienced a patient who are diagnosed aCML and transformed to myeloid blast crisis after 17 months. Monosomy 7 and deletion of 12p were found on conventional cytogenetics.
Keywords: Atypical chronic myelogenous leukemia, Myeloid blast crisis, Monosomy 7, Deletion of 12p
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