Korean J Hematol 2007; 42(2):
Published online June 30, 2007
https://doi.org/10.5045/kjh.2007.42.2.146
© The Korean Society of Hematology
김훈구, 이경원, 김광민, 강명희, 주지현, 강정훈, 이종석
경상대학교 의과대학 내과학교실,
분당서울대학교병원 내과
Pure red cell aplasia (PRCA) is a rare hematologic disorder characterized by anemia, reticulocytopenia in the blood and isolated severe erythroblastopenia with no abnormalities of the granulopoiesis and megakaryopoiesis in the bone marrow. Acquired PRCA has been reported in association with various autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis, mixed connective tissue disease and Sjögren's syndrome. We report here on a case of PRCA associated with Hashimoto disease (without any other autoimmune disease) which, to the best of our knowledge, has not been previously reported in Korean and English literatures. Our patient was treated with levothyroxine alone without other immunosuppressive agents and her hemoglobin concentration and hematocrit values returned to normal.
Keywords Pure red cell aplasia, Hashimoto disease, Autoimmune, Hypothyroidism
Korean J Hematol 2007; 42(2): 146-150
Published online June 30, 2007 https://doi.org/10.5045/kjh.2007.42.2.146
Copyright © The Korean Society of Hematology.
김훈구, 이경원, 김광민, 강명희, 주지현, 강정훈, 이종석
경상대학교 의과대학 내과학교실,
분당서울대학교병원 내과
Hoon Gu Kim, Gyeong Won Lee, Kwang Min Kim, Myung Hee Kang, Ji Hyun Ju, Jung Hun Kang, Jong Seok Lee
Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju,
Seoul National University Bundang Hospital, Seongnam, Korea
Pure red cell aplasia (PRCA) is a rare hematologic disorder characterized by anemia, reticulocytopenia in the blood and isolated severe erythroblastopenia with no abnormalities of the granulopoiesis and megakaryopoiesis in the bone marrow. Acquired PRCA has been reported in association with various autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis, mixed connective tissue disease and Sjögren's syndrome. We report here on a case of PRCA associated with Hashimoto disease (without any other autoimmune disease) which, to the best of our knowledge, has not been previously reported in Korean and English literatures. Our patient was treated with levothyroxine alone without other immunosuppressive agents and her hemoglobin concentration and hematocrit values returned to normal.
Keywords: Pure red cell aplasia, Hashimoto disease, Autoimmune, Hypothyroidism
Seok In Hong, Myoung Joon Song, Yeon Seong Kim, Tae Hun Kim, Seok Goo Cho, Dong Gun Lee, Hae Kyung Lee
Korean J Hematol 2004; 39(3): 191-195Jae Lyun Lee, Hee Jung Kang, Hyun Ah Oh, Gu Lee, Kyung Hee Lee, Myung Soo Hyun, Hyun Mo Ryoo
Korean J Hematol 2002; 37(1): 60-64Young Jin Lee, Byung Jun So, Kwon Mook Chae, Byung Hak Jeong
Korean J Hematol 1999; 34(4): 646-650