Korean J Hematol 1998; 33(3):
Published online September 30, 1998
© The Korean Society of Hematology
철결핍성 빈혈과 동반되어 낮은 평균적혈구용적을 보인 비타민 Bl2 결핍성 빈혈 1례
이성배, 김정희, 황인후, 김영훈, 공수정, 손향은
을지의과대학 노원을지병원 혈액종양내과,
을지의과대학 노원을지병원 임상병리과
A Case of Vitamin B12 Deficiency Anemia with Low MCV Combined with Iron Deficiency Anemia
Vitamin B12 deficiency anemia is a disorder caused by impaired DNA synthesis. Vitamin B12 binds to the intrinsic factor produced by the parietal cells and is absorbed in the distal ileum. After total gastrectomy, megaloblastic anemia is developed due to the absence or deficiency of the intrinsic factor. Concomitant
iron deficiency states such as various malabsorption syndromes and alcoholism induce that the bone marrow erythroid megaloblastosis and peripheral blood macroovalocytosis are masked because of countervailing the tendency of iron deficiency to produce microblasts and hypochromic microcytic erythrocytes.
We experienced a case of Vitamin B12 deficiency anemia with low RBC mean corpuscular volume(MCV) due to combined with iron deficiency anemia in 42 year-old female patient and report the case with literature review.
Keywords Iron deficiency Anemia; Low MCV; Vitamin B12 deficiency anemia;
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Korean J Hematol 1998; 33(3): 427-431
Published online September 30, 1998
Copyright © The Korean Society of Hematology.
철결핍성 빈혈과 동반되어 낮은 평균적혈구용적을 보인 비타민 Bl2 결핍성 빈혈 1례
이성배, 김정희, 황인후, 김영훈, 공수정, 손향은
을지의과대학 노원을지병원 혈액종양내과,
을지의과대학 노원을지병원 임상병리과
A Case of Vitamin B12 Deficiency Anemia with Low MCV Combined with Iron Deficiency Anemia
Suug Bae Lee, Jeong Hee Kim, In Hu Hwang, Young Hoon Kim, Soo Jung Gong, Hyang Eun Sohn
Department of Internal Medicine, Clinical Pathology, Nowon Eulji Hospital, Eulji Medical College, Seoul, Korea
Abstract
Vitamin B12 deficiency anemia is a disorder caused by impaired DNA synthesis. Vitamin B12 binds to the intrinsic factor produced by the parietal cells and is absorbed in the distal ileum. After total gastrectomy, megaloblastic anemia is developed due to the absence or deficiency of the intrinsic factor. Concomitant
iron deficiency states such as various malabsorption syndromes and alcoholism induce that the bone marrow erythroid megaloblastosis and peripheral blood macroovalocytosis are masked because of countervailing the tendency of iron deficiency to produce microblasts and hypochromic microcytic erythrocytes.
We experienced a case of Vitamin B12 deficiency anemia with low RBC mean corpuscular volume(MCV) due to combined with iron deficiency anemia in 42 year-old female patient and report the case with literature review.
Keywords: Iron deficiency Anemia, Low MCV, Vitamin B12 deficiency anemia,
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