Primary CNS lymphoma: latest updates and a 10-year monocenter experience

Emanuele Cencini; Alberto Fabbri; Luana Schiattone; Alfonso Cerase; Monica Bocchia

doi:10.5045/br.2018.53.2.174

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Letter to the Editor

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Blood Res 2018; 53(2):

Published online June 25, 2018

https://doi.org/10.5045/br.2018.53.2.174

Primary CNS lymphoma: latest updates and a 10-year monocenter experience

Emanuele Cencini^1*, Alberto Fabbri¹, Luana Schiattone¹, Alfonso Cerase², and Monica Bocchia¹

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¹Unit of Hematology, Azienda Ospedaliera Universitaria Senese and University of Siena, Siena, Italy.

²Unit of Neuroimaging and Neurointervention, Department of Neurological and Sensorineural Sciences, Azienda Ospedaliera Università Senese, Santa Maria alle Scotte University and NHS Hospital, Siena, Italy.

Correspondence to : Emanuele Cencini. Unit of Hematology, Azienda Ospedaliera Universitaria Senese and University of Siena, Viale Bracci, 16-53100 Siena, Italy. cencioema@libero.it

Received: December 13, 2017; Revised: January 3, 2018; Accepted: February 22, 2018

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article

Letter to the Editor

Blood Res 2018; 53(2): 174-177

Published online June 25, 2018 https://doi.org/10.5045/br.2018.53.2.174

Primary CNS lymphoma: latest updates and a 10-year monocenter experience

Emanuele Cencini^1*, Alberto Fabbri¹, Luana Schiattone¹, Alfonso Cerase², and Monica Bocchia¹

¹Unit of Hematology, Azienda Ospedaliera Universitaria Senese and University of Siena, Siena, Italy.

Correspondence to:Emanuele Cencini. Unit of Hematology, Azienda Ospedaliera Universitaria Senese and University of Siena, Viale Bracci, 16-53100 Siena, Italy. cencioema@libero.it

Received: December 13, 2017; Revised: January 3, 2018; Accepted: February 22, 2018

Fig 1.

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Figure 1.Progression-free survival (PFS) among primary central nervous system lymphoma (PCNSL) patients receiving ≥2 treatment cycles vs. those who underwent early discontinuation.

Blood Research 2018; 53: 174-177https://doi.org/10.5045/br.2018.53.2.174

Table 1 . Patients' characteristics..

Abbreviations: B2M, beta-2-microglobulin; LDH, lactate dehydrogenase; PS, performance status..

Table 2 . Responses to treatment and outcomes..

Abbreviations: ASCT, autologous stem cell transplantation; CR, complete response; ORR, overall response rate; PD, progressive disease; WBRT, whole brain radiotherapy..

Table 3 . Treatment toxicity..

Abbreviation: WBRT, whole-brain radiotherapy..