Proteomic analysis for the identification of candidate biomarkers for FR exposure. Two-dimensional electrophoresis showed altered expression of various protein spots (upper panel), which are quantified as bar graphs (lower panel) of relative quantitative expression of each candidate proteomic marker. Four altered spots (147, 172, 220, and 581, red boxes) were identified as annexin A6, pyruvate kinase protein, UDP-glucose dehydrogenase, and phospholipase A2.