CONSORT diagram of the patients included in analysis.

Abbreviations: ADAMTS13, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13; aHUS, atypical hemolytic uremic syndrome; PEX, plasma exchange; STEC-HUS, Shiga-like toxin-producing E. coli hemolytic uremic syndrome; TMA, thrombotic microangiopathy; TTP, thrombotic thrombocytopenic purpura.