Abbreviations: ASCT, autologous stem cell transplantation; CR, complete response; CSF, cerebrospinal fluid; ECOG, Eastern Cooperative Oncology Group; IELSG, International Extranodal Lymphoma Study Group; KPS, Karnofsky Performance Status; LDH, lactate dehydrogenase; MSKCC, Memorial Sloan-Kettering Cancer Center; NE, not evaluable; PD, progressive disease; PR, partial response; RT, radiotherapy; SD, stable disease; WBRT, whole brain radiotherapy.